reply to: mucosal histopathology in celiac disease: a rebuttal of oberhuber´s subdivision of marsh iii
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Reply to: Mucosal histopathology in celiac disease: a rebuttal of Oberhuber´s subdivision of Marsh III
We read with interest the paper entitled “Mucosal histopathology in celiac disease: a rebuttal of Oberhuber ́s sub-division of Marsh III” by MN Marsh et al. published in this Journal (1). We have proposed a standardized classification system of the celiac lesions in 1999 (2).In their paper Marsh et al. comment on this work. To our surprise, the authors of the paper suggest that the flat mucosa (...
متن کاملMucosal histopathology in celiac disease: a rebuttal of Oberhuber’s sub-division of Marsh III
Individuals with particular genetic backgrounds develop immune responses to wheat proteins and become 'gluten-sensitised'. Mucosal pathology arises through activated mucosal T lymphocytes, resulting in a graded, adverse reaction between particular genes and wheat proteins. Given these varied influences, the Marsh Classification broadly itemises those stages through which a normal mucosa (Marsh ...
متن کاملmucosal histopathology in coeliac disease: a rebuttal of oberhuber’s sub-division of marsh iii
individuals with particular genetic backgrounds develop immune responses to wheat proteins and become ‘gluten-sensitised’. mucosal pathology arises through activated mucosal t lymphocytes, resulting in a graded, adverse e reaction between particular genes and wheat proteins. given these varied influences, the marsh classification broadly itemises those stages through which a normal mucosa (mars...
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chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...
15 صفحه اولWhat is the best histopathological classification for celiac disease? Does it matter?
The rebuttal of Oberhuber’s sub-division of Marsh III type in celiac disease (1) and its subsequent correspondence in the past and present issues of GHFBB allow us to review the current thinking on the histopathological classification of celiac disease. In the Definition of Medicine, Avicenna argues: -“While some divide medicine into a theoretical and a practical [applied] science, others may a...
متن کاملOberhuber versus Marsh: much ado about nothing?
This issue of the journal features a spirited debate between Oberhuber and Marsh et al regarding the existence and significance of Oberhuber’s sub-classification of the Marsh III lesion into III a, b, c categories. The controversy stems from an article by Marsh and colleagues in an earlier issue of this journal where they present scanning electron microscopic (SEM) images from two cases classif...
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عنوان ژورنال:
gastroenterology and hepatology from bed to benchجلد ۸، شماره ۴، صفحات ۲۰۱۵-۸
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